Apoptosis Reagents and Kits

Assays, reagents, kits, and other assorted products used to detect cellular apoptosis, determine the activity levels of caspase or cathepsin, or identify similar cellular activity.

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196 – 210 of 1,815 results

196

AdipoGen GANT61,Chemical. CAS: 500579-04-4

GANT61, AdipoGen Life Sciences. Chemical. CAS: 500579-04-4. Formula: C27H35N5. MW: 429.6. Cell permeable GLI antagonist. Inhibits Gli1 and Gli2-induced transcription. Sonic hedgehog (Shh) signaling pathway inhibitor, downstream of SMO and SUFU. Displays antiproliferative and antitumor activity in vitro and in vivo. Apoptosis inducer. 500579-04-4

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197

STEMCELL Technologies Annexin V, PE, Size: 100 Tests

Annexin V is a member of the annexin family of proteins that bind to membrane phospholipids in the presence of calcium. This dye has high affinity for phosphatidylserine (PS) that is present in the inner leaflet of the plasma membrane. Verified for use with flow cytometry assays use this antibody to detect the translocation of PS to the external environment. Annexin V is used along with viability dyes such as 7-AAD (Catalog 75001) or Propidium Iodide (Catalog 75002). The process of PS translocation occurs prior to the loss of membrane integrity. Therefore as cells progress through apoptosis and towards necrosis the cell membrane is compromised and consequently viability dyes pass into the cell. Thus cells undergoing early apoptosis stain positive for Annexin V and negative for viability dyes while apoptotic death or necrosis is characterized by positive staining for both Annexin V and the viability d

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198

American Research Products Inc HE STAINING KIT

5000264961 HE STAINING KIT

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199

Alkali Scientific In-Situ Adapter for Use with Combination Blocks

InSitu adapter fits on the TC 9639 Thermal Cycler block and holds 4 standard slides. Compatible with: T5000-96 and T5000-384.

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200

Biotium Dual Apoptosis Assay with NucView 488 caspase-3 Substrate and Texas Red-Annexin V (50 - 250 assays)

These kits provides two apoptosis markers, our novel NucView 488 Caspase-3 Substrate and Annexin V conjugated with a dye, for profiling apoptotic cells and studying the relation of two important apoptosis events, caspase-3 activation and phosphatidylserine (PS) translocation. Annexin V conjugation for the second marker is available with the following dyes: Sulforhodamine 101 (Texas Red) Annexin V, CF594 Annexin V, and CF640R Annexin V. Unlike conventional caspase assays, NucView 488 Caspase-3 substrate detects caspase-3 activity within individual whole cells in a non-interfering manner. The substrate, which is both non-fluorescent and nonfunctional as a DNA dye, rapidly crosses cell membranes to enter the cytoplasm, where it is cleaved by caspase-3 to form a high-affinity DNA dye that stains the nucleus bright green. The kit contains reagents sufficient for 50 flow cytometry assays (200 uL assay volume).